Yes, smoking significantly impacts the effectiveness of Tepezza (teprotumumab) treatment for thyroid eye disease. Research has shown that people who smoke while receiving Tepezza treatment experience less improvement in their TED symptoms compared to non-smokers. Smoking is particularly problematic because it restricts Show Full Answer
Yes, smoking significantly impacts the effectiveness of Tepezza (teprotumumab) treatment for thyroid eye disease. Research has shown that people who smoke while receiving Tepezza treatment experience less improvement in their TED symptoms compared to non-smokers. Smoking is particularly problematic because it restricts blood vessels and reduces oxygen flow to eye tissues, causing inflammation. This not only makes TED symptoms worse but also interferes with how well anti-inflammatory medications like Tepezza can work. For the best possible treatment outcomes, it's crucial to quit smoking if you're planning to start or are currently receiving Tepezza treatment.
May 26, 2025